Randomized, blinded, 3-arm clinical trial assessing optimal temperature and duration for treatment with minimally invasive fractional radiofrequency
In this study, subjects were allocated to three study arms and underwent single-pass fractional RF Profound treatment. Three physicians assed digital photos to determine significantly positive results.
PubMed Reference:Alexiades M, Berube D. Dermatol Surg. 2015 May;41(5):623-32.
Study Details:
- 15 subjects allocated to 3 study arms (Table 1)
- Single-pass fractional RF (FRF) Profound treatment
- 3 physicians - blinded assessment of digital photos
Study Results:
- Optimal treatment settings of 67°C and 3-4 seconds confirmed
- 100% response rate for rhytides (Fitzpatrick Wrinkle Scale) at 67°C
- Continued improvement up to 6 months post-treatment
- May yield>37% improvement of lower surgical face-lift
- Simplicity, 32-minute average duration & safety profile (no significant adverse events)
- important in cost-benefit analysis compared to face-lift