Noninvasive body contouring by focused ultrasound: Safety and efficacy of the contour device in a multicenter, controlled, clinical study

Reference:Teitelbaum SA, Burns JL, Kubota J, et al. Plast Reconstr Surg. 2007 Sep;120(3):779-89.

Study Details:

• 164 healthy adults (137 subjects in the experimental group and 27 in the control, untreated group) at 5 sites
• 1 treatment to the abdomen, thighs, or flanks
• Circumference and fat thickness were measured at 12 weeks
• Circumference reduction was compared with the untreated group and with an untreated area (thigh) within the treated group
• Laboratory testing (including serum lipids), pulse oximetry, and liver ultrasound

Study Results:

• Mean reduction of 1.9 cm in treated area circumference (abdomen -2.3 cm, flanks -1.8 cm, thighs -1.6 cm)
• Mean reduction of 2.9 mm in skin fat thickness
• The majority of the effect was achieved within 2 weeks and was sustained at 12 weeks
• Within the control group, no statistical differences in the mean circumference reduction from baseline
• No clinically significant changes in the measured laboratory parameters
• 7 adverse events were reported, all of which were anticipated, mild, and resolved within the study period