Profound®


Masterfully rebuild the skin matrix

Up to 5x more elastin, up to 2x more collagen, and increased hyaluronic acid.1,2

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What is Profound

The Profound system is the first and only radiofrequency (RF) microneedling device with FDA clearance for face and body.4 A non-surgical alternative to address aging skin, the Profound system uses RF energy to provide long-lasting facial wrinkle reduction and improve the appearance of cellulite.4,5

How it works

Dermal module for facial wrinkles

Bipolar RF energy delivered to deep reticular dermis provides thermal damage to dermis without thermal impact on epidermis.

Subcutaneous module for cellulite

Bipolar RF energy targets deeper skin layers to coagulate adipose tissue and remodel cellulite.

Profound Applications
  • Electrocoagulation and haemostasis
  • Percutaneous wrinkle reduction
  • Cellulite reduction
  • Electrocoagulation and haemostasis
  • Percutaneous wrinkle reduction
  • Cellulite reduction
System Highlights

Profound RF is a one-of-a-kind wrinkle and cellulite treatment system


8 facts that make this a one-of-a-kind, must-have system.

  • Clinically proven to create all 3 skin fundamentals: up to 5x more elastin, up to 2x more collagen, and increased hyaluronic acid1,4
  • First and only machine that combine microneedle with radio frequency (RF), with FDA clearance for face and body4
  • Just one non-surgical treatment required to achieve lasting results2,4,5,6
  • 100% response rate for facial wrinkles5,7
  • 94% response rate for improvement in the appearance of cellulite4,7,8
  • Reduces the appearance of cellulite severity with only one non-surgical treatment4,8,9
  • The only real-time, temperature-controlled RF microneedling device4
  • Proven in 8 comprehensive clinical studies10

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Treatment Results

Look at the difference a few treatments can make.

Profound-skin-rejuvenation-Steve-Eubanks-MD
Before
After
Photos courtesy of: Steve Eubanks, MD
Profound
Profound-skin-rejuvenation-David-deJongh-MD
Before
After
Photos courtesy of: David de Jongh, MD
Profound
Profound-cellulite-Leyda-Bowes-MD
Before
After
Photos courtesy of: Leyda Bowes, MD
Profound
Profound-skin-elasticity-Nima-Naghshineh-MD
Before
After
Photos courtesy of: Nima Naghshineh, MD, M.Sc.
Profound
Profound-skin-elasticity-Nima-Naghshineh-MD-3m-1tx
Before
After
Photos courtesy of: Nima Naghshineh, MD, M.Sc.
Profound
Profound-skin-elasticity-Macrene-Alexiadies-MD-P1-3m-1tx
Before
After
Photos courtesy of: Macrene Alexiadies, MD
Profound
Profound-skin-elasticity-Ben-Talei-MD-P1
Before
After
Photos courtesy of: Ben Talei, MD
Profound
Profound-skin-elasticity-Ben-Talei-MD-P2-1tx
Before
After
Photos courtesy of: Ben Talei, MD
Profound
Profound-cellulite-Tara-Delle-Chiaie-MSN-4m-1tx
Before
After
Photos courtesy of: Tara Delle Chiaie, MSN
Profound
Key Benefits

Why consider the Profound system?

Patients seek treatments that:


  • Are less painful and invasive than surgery
  • Offer an alternative to the use of toxins and fillers
  • Require more manageable downtime

The Profound system enhances aesthetics practices by providing a clinically proven, nonsurgical, single-treatment procedure.1-3

The Profound system can help your practice to fill the treatment gap that exists between dermal injectables and invasive surgery.

  • Adopt new patients in advance of surgery
  • Retain existing patients who are not ready for surgical procedures
  • Increase revenue with complementary treatments and future procedures

Bottom line: The Profound system enhances aesthetics practices by providing a clinically proven, non-surgical, single-treatment procedure1,4,5 that requires less practice expense and patient downtime.

Testimonials

Physician's Perspective


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Let a Candela product expert show you how the Profound system can help transform your patients - and your practice.

 
System Specifications
Bi-polar Radio Frequency 460 ± 5 kHz
Maximum Output Voltage 84 VRMS; 5W per channel
Channels Dermal - 5 independent pairs of bi-polar micro-needles
SubQ - 7 independent pairs of bi-polar micro-needles
Mode PID temperature control
Target Temperature Range 65-75˚C (149 – 167˚F) ± 1˚C
Treatment Duration 3-5 seconds, 0.2 second increments
User Interface GUI – color touch screen
System Dimensions 125 x 46.5 x 44.5 centimeters
29.5 x 18.5 x 17.5 inches
System Weight 23 kg / 55 lbs
Electrical Requirements 100 – 240 VAC; 2.5 A; 50-60 Hz; single phase
References
1. Hantash BM, Ubeid AA, Chang H, Kafi R, Renton B. Bipolar fractional radiofrequency treatment induces neoelastogenesis and neocollagenesis. Lasers Surg Med. 2009;41(1):1-9.
2. Willey A, Kilmer S, Newman J, et al. Elastometry and clinical results after bipolar radiofrequency treatment of skin. Dermatol Surg. 2010;36(6):877-884.
3. Howard D. Structural changes associated with aging skin. The International Dermal Institute website. Available at: http://www.dermalinstitute.com/us/library/11_article_ Structural_Changes_AssociatAs_with_Aging_Skin.html.
4. Profound 510(k) clearance (K161043), September 2016.
5. Alexiades-Armenakas M, Newman J, Willey A, et al. Prospective multicenter clinical trial of a minimally invasive temperature-controlled bipolar fractional radiofrequency system for rhytid and laxity treatment. Dermatol Surg. 2013;39(2):263-273.
6. Alexiades M, Berube D. Randomized, blinded, 3-arm clinical trial assessing optimal temperature and duration for treatment with minimally invasive fractional radiofrequency. Dermatol Surg. 2015;41(5):623-632.
7. Data on file. Individual results may vary.
8. Rate for independent thigh assessment. Patients with Fitzpatrick skin types I-III were assessed for improvement in dimples and undulation irregularities. The mean pain level reported was 3.74 on a 10-point scale. Anticipated treatment responses such as erythema and edema were reported and were completely resolved without medical intervention.4
9. Alexiades M, Munavalli G, Goldberg D, Berube D. Prospective multicenter clinical trial of a temperature-controlled subcutaneous microneedle fractional bipolar radiofrequency system for the treatment of cellulite. Dermatologic Surgery 44(10):p 1262-1271, October 2018. | DOI: 10.1097.
10. Candela, data on file.
11. Berube D. How Profound effectively treats cellulite via collagenesis and elastogenesis. 2016.
12. American Society for Aesthetic Plastic Surgery. 2017 Cosmetic Surgery National Data Bank Statistics.
13. American Society for Aesthetic Plastic Surgery. 2016 Cosmetic Surgery National Data Bank Statistics.
1. Hantash BM, Ubeid AA, Chang H, Kafi R, Renton B. Bipolar fractional radiofrequency treatment induces neoelastogenesis and neocollagenesis. Lasers Surg Med. 2009;41(1):1-9.
2. Willey A, Kilmer S, Newman J, et al. Elastometry and clinical results after bipolar radiofrequency treatment of skin. Dermatol Surg. 2010;36(6):877-884.
3. Howard D. Structural changes associated with aging skin. The International Dermal Institute website. Available at: http://www.dermalinstitute.com/us/library/11_article_ Structural_Changes_AssociatAs_with_Aging_Skin.html.
4. Profound system Australian Register of Therapeutic Goods (ARTG) clearance (ARTG 189698).
5. Alexiades-Armenakas M, Newman J, Willey A, et al. Prospective multicenter clinical trial of a minimally invasive temperature-controlled bipolar fractional radiofrequency system for rhytid and laxity treatment. Dermatol Surg. 2013;39(2):263-273.
6. Alexiades M, Berube D. Randomized, blinded, 3-arm clinical trial assessing optimal temperature and duration for treatment with minimally invasive fractional radiofrequency. Dermatol Surg. 2015;41(5):623-632.
7. Data on file. Individual results may vary.
8. Rate for independent thigh assessment. Patients with Fitzpatrick skin types I-III were assessed for improvement in dimples and undulation irregularities. The mean pain level reported was 3.74 on a 10-point scale. Anticipated treatment responses such as erythema and edema were reported and were completely resolved without medical intervention.4
9. Alexiades M, Munavalli G, Goldberg D, Berube D. Prospective multicenter clinical trial of a temperature-controlled subcutaneous microneedle fractional bipolar radiofrequency system for the treatment of cellulite. Dermatologic Surgery 44(10):p 1262-1271, October 2018. | DOI: 10.1097.
10. Candela, data on file.
11. Berube D. How Profound effectively treats cellulite via collagenesis and elastogenesis. 2016.
12. American Society for Aesthetic Plastic Surgery. 2017 Cosmetic Surgery National Data Bank Statistics.
13. American Society for Aesthetic Plastic Surgery. 2016 Cosmetic Surgery National Data Bank Statistics.
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