Profound®

You may not want a facelift, but you'll want this.


The Profound treatment is clinically proven to create younger, smoother-looking skin with only one nonsurgical procedure.*

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What is Profound

The Profound treatment is a nonsurgical alternative for treating facial wrinkles and the appearance of cellulite. It combines radiofrequency (RF) energy with ultrafine needles (microneedles) to renew your skin from within. Healthcare providers across the globe rely on the Profound treatment to provide lasting wrinkle and/or cellulite reduction for their patients.

Profound treatment

How it works

A single Profound treatment stimulates your body to naturally reproduce collagen, elastin, and hyaluronic acid to revitalize the skin and build new, healthy tissue. The Profound treatment is clinically proven to stimulate your body’s own wound-healing response to reduce the signs of aging without the use of chemicals or surgery.

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Treatment Highlights
wrinkle treatment

Facial Wrinkles


As we age, our skin begins to lose its elasticity and becomes more fragile. This is a result of our body's collagen levels decreasing, elastin production stopping and hyaluronic acid diminishing.4,12-14

The Profound treatment awakens your body’s own natural healing process by stimulating the production of these three skin elements to create younger-looking skin.3,5,*

cellulite treatment

Cellulite Appearance


Dimpling of the skin, referred to as cellulite, is no match for the Profound treatment. The Profound treatment delivers fractional RF energy to the subcutaneous layer of tissue. Studies demonstrate a 94% improvement in cellulite severity from a single treatment.2,*

Treatment Results

Profound-skin-rejuvenation-Steve-Eubanks-MD
Before
After
Photos courtesy of: Steve Eubanks, MD
Condition: Skin Elasticity
Treated with: Profound
Profound-skin-rejuvenation-David-deJongh-MD
Before
After
Photos courtesy of: David de Jongh, MD
Condition: Skin Elasticity
Treated with: Profound
Profound-cellulite-Leyda-Bowes-MD
Before
After
Photos courtesy of: Leyda Bowes, MD
Condition: cellulite
Treated with: Profound
Profound-skin-elasticity-Nima-Naghshineh-MD
Before
After
Photos courtesy of: Nima Naghshineh, MD, M.Sc.
Condition: Skin Elasticity
Treated with: Profound
Profound-skin-elasticity-Nima-Naghshineh-MD-3m-1tx
Before
After
Photos courtesy of: Nima Naghshineh, MD, M.Sc.
Condition: Skin Elasticity
Treated with: Profound
Profound-skin-elasticity-Macrene-Alexiadies-MD-P1-3m-1tx
Before
After
Photos courtesy of: Macrene Alexiadies, MD
Condition: Skin Elasticity
Treated with: Profound
Profound-skin-elasticity-Ben-Talei-MD-P1
Before
After
Photos courtesy of: Ben Talei, MD
Condition: Skin Elasticity
Treated with: Profound
Profound-skin-elasticity-Ben-Talei-MD-P2-1tx
Before
After
Photos courtesy of: Ben Talei, MD
Condition: Skin Elasticity
Treated with: Profound
Profound-cellulite-Tara-Delle-Chiaie-MSN-4m-1tx
Before
After
Photos courtesy of: Tara Delle Chiaie, MSN
Condition: cellulite
Treated with: Profound
Key Benefits

Just one treatment


The Profound system is an energy-based solution that produces a 100% response rate to facial wrinkles and a 94% improvement in cellulite severity with only one treatment.2,3,* The end result is younger, smoother-looking skin – with minimal downtime.2,3,5,8

No surgery


Surgery is not the only option to reduce the signs of aging. The Profound treatment is a single treatment, nonsurgical alternative to a facelift or surgical cellulite reduction.

Long lasting results


It awakens your body’s own natural healing process by stimulating the production of 3 skin elements: collagen, elastin, and hyaluronic acid.1,5 These 3 elements create lasting volume and firmness for smoother-, younger-looking skin.15-17

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FAQs

The Profound treatment is a nonsurgical alternative for treating facial wrinkles and the appearance of cellulite. It combines radiofrequency (RF) energy with ultrafine needles (microneedles) to renew your skin from within. Healthcare providers across the globe rely on the Profound treatment to provide lasting wrinkle and/or cellulite reduction for their patients.

It delivers precise temperatures to the deep layers of your skin, exactly where energy delivery is most beneficial. This energy breaks down tissue in order to trigger your body’s natural healing process, stimulating your body to naturally create new elastin, collagen and hyaluronic acid to revitalize the skin and build new, healthy tissue.

This is the only RF injectable energy treatment that stimulates and triggers the creation of new elastin, collagen, and hyaluronic acid—the 3 skin fundamentals for smooth, youthful-looking skin. The Profound treatment is what helps patients get the snap back to their aging skin.

These 3 skin fundamentals are important in keeping our skin strong, elastic, and flexible. When their levels drop, facial wrinkles may appear:

  • Collagen is the glue that holds our skin together.
  • Elastin helps skin to return to its original position when it is poked or pinched. Not unlike a rubber band, elastin is what gives the snap to your skin.
  • Hyaluronic acid is a gel-like liquid that improves skin hydration, stimulates the production of collagen, and helps skin to maintain its elasticity.

The Profound treatment stimulates the body to create new elastin to bring the snap back to aging skin, collagen to revitalize your skin, and hyaluronic acid—all in a single treatment.

Prior to treatment, you will have a personalized Profound treatment consultation to determine your goals and to establish the target area for treatment. On the day of your treatment, a local anesthetic may be applied to help you manage comfort. We’ll administer treatment with the Profound system handpiece, which will deliver pulses of energy to the targeted areas.

Total treatment time is approximately 1 hour, depending on the treatment area.
Typically, patients can return to their normal activities within 24 hours after treatment. We’ll discuss your individual care plan and recovery during your initial consultation.

After your Profound treatment for facial wrinkle reduction, you may experience minor swelling or bruising. In clinical studies, these events resolved within 5 to 10 days, depending on treatment area and anesthesia protocol.

After your Profound treatment for improving the appearance of cellulite, you may experience some redness and soreness on the treated area. In clinical studies, these side effects were mild and resolved on their own.

The Profound treatment is clinically proven to create smooth, younger-looking skin with only 1 nonsurgical treatment. In clinical studies, it was shown to reduce facial wrinkles in 100% of patients and 94% of treated thighs showed an improvement in cellulite appearance after 1 treatment.

No, the Profound treatment is not plastic surgery, nor is it a facelift. It is a nonsurgical procedure that offers lasting results.

Yes, the Profound treatment could help to complement your prior cosmetic surgery results.

No, the Profound treatment is great for both the early signs of aging like fine lines and more advanced signs of aging like deep wrinkles. With the Profound treatment you can delay the signs of aging the natural way, for smooth, younger-looking skin.

One Profound treatment is all it takes to help you delay the signs of aging.

A single Profound treatment stimulates your body to naturally reproduce collagen, elastin, and hyaluronic acid to revitalize the skin and build new, healthy tissue. The Profound treatment is clinically proven to stimulate your body’s own wound-healing response to reduce the signs of aging without the use of chemicals or surgery.

References
*Data on file. Individual results may vary.
1. Hantash BM, Ubeid AA, Chang H, Kafi R, Renton B. Bipolar fractional radiofrequency treatment induces neoelastogenesis and neocollagenesis. Lasers Surg Med. 2009;41(1):1-9.
2. Profound 510(k) clearance (K161043), September 2016.
3. Alexiades-Armenakas M, Newman J, Willey A, et al. Prospective multicenter clinical trial of a minimally invasive temperature-controlled bipolar fractional radiofrequency system for rhytid and laxity treatment. Dermatol Surg. 2013;39(2):263-273.
4. Howard D. Structural changes associated with aging skin. The International Dermal Institute website. http://www.dermalinstitute.com/us/library/11_article_Structural_Changes_AssociatAs_with_Aging_Skin.html. Accessed August 31, 2018. 5. Willey A, Kilmer S, Newman J, et al. Elastometry and clinical results after bipolar radiofrequency treatment of skin. Dermatol Surg. 2010;36(6):877-884.
6. Alexiades M, Berube D. Randomized, blinded, 3-arm clinical trial assessing optimal temperature and duration for treatment with minimally invasive fractional radiofrequency. Dermatol Surg. 2015;41(5):623-632
7. Candela, data on file.
8. Berube D. How Profound effectively treats cellulite via collagenesis and elastogenesis. 2016. Candela, data on file.
9. Berube D. Real-time temperature feedback for clinical reproducibility: the mechanism of action of Profound. 2015. Candela, data on file.
10. Alexiades-Armenakas M, Rosenberg D, Renton B, Dover J, Arndt K. Blinded, randomized, quantitative grading comparison of minimally invasive, fractional radiofrequency and surgical face-lift to treat skin laxity. Arch Dermatol. 2010;146(4):396-405.
11. Alexiades M, Munavalli G, Goldberg D, Berube D. Prospective multicenter clinical trial of a temperature-controlled subcutaneous microneedle fractional bipolar radiofrequency system for the treatment of cellulite. Dermatol Surg. 2018;1-10. doi: 10.1097.
12. McIntosh J. Collagen: what is it and what are its uses? Medical News Today website. https://www.medicalnewstoday.com/articles/262881.php. Accessed November 13, 2018.
13. Elastin (medical definition). MedicineNet website. https://www.medicinenet.com/script/main/art.asp?articlekey=24541. Accessed November 13, 2018.
14. Hyaluronic acid (medical definition). MedicineNet website. https://www.medicinenet.com/script/main/art.asp?articlekey=25768. Accessed November 13, 2018.
15. Luebberding S, Krueger N, Sadick NS. Cellulite: an evidence-based review. Am J Clin Dermatol. 2015;16(4):243-256.

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