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101 results
Clinical Papers

A Larger Spot Size Does Enhance Penetration and Efficacy in the Treatment of Port-Wine Stains

June 1, 2020
Two case studies of a laser-resistant port-wine stain (PWS) previously treated with pulsed dye laser and maximum spot size of 10 mm. Marked lightening of the PWS with no epidermal injury was observed in a skin type III male and laser-resistant PWS improvement in a skin type IV male, following 2 monthly Vbeam Prima treatments with the large 15 mm spot size.
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Clinical Papers

Histological Characterization of Age-Related Skin Changes Following the Use of Picosecond Laser: Low Versus High Energy

May 21, 2020
28 women with photodamage underwent a picosecond laser treatment with the Resolve 1064 nm handpiece, using low energy fluence of 1.1 J/cm2 or high energy treatment (2.1 J/cm2). High energy group showed significant improvement with a more pronounced effect on facial skin than low energy treatments. Histopathological examination of biopsies at 3 weeks’ post-treatment showed a marked elevation in collagen type III expression antibodies in the high fluence group.
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Clinical Papers

A Randomized, Split-Face, Double-Blind Comparison Trial Between Fractionated Frequency-Doubled 1064/532 Nm Picosecond Nd:YAG Laser and Fractionated 1927 Nm Thulium Fiber Laser for Facial Photorejuvenation

April 14, 2020
20 subjects were randomly assigned to split-face treatment with PicoWay Resolve (532/1064 nm picosecond lasers) treatment to one side of the face and 1927 nm fractionated thulium fiber laser (TFL) to the contralateral side. Blinded, non‐treating evaluator assessments of photodamage at 6-month follow-up showed statistically significant improvements in photodamaged skin in both treatment groups, but with less downtime associated with Resolve treatments.
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Clinical Papers

The Efficacy of Pulsed Dye Laser Pretreated With or Without Local Anesthetic on Patients Presenting With Erythema of Face, Neck, Chest, and Extremities

April 1, 2020
Retrospective study of 69 subjects with erythema from various skin conditions including telangiectasia, cherry angioma, striae, and rosacea. 31 patients were pretreated with topical anesthetics before 1-6 Vbeam treatments, while 38 patients had no pretreatment anesthetic. Improvement was observed in both groups by blinded dermatologists, with no significant difference between groups.
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Clinical Papers

The First Commercial 730 nm Picosecond-Domain Laser is Safe and Effective for Treating Multicolor Tattoos

March 24, 2020
This study examined several males and females who had tattoos removed thanks to treatment from a 730 nm titanium-sapphire laser-pumped laser. A blind assessment showed clearance in varying degrees for six different colors of pigments without scarring or pigmentary alteration.
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Clinical Papers

Successful treatment of pigmentary disorders in Asians with a novel 730-nm picosecond laser

March 14, 2020
Two Korean females with multiple freckles on the face (Case 1) and melasma, freckles, lentigines and erythema (Case 2) underwent a single PicoWay 730 nm picosecond laser treatment and were evaluated at 6 weeks post‐treatment. Independent evaluation of global assessment, by 2 dermatologists, indicated excellent response (75–94% lightening) for Case 1 and good response (50–74% lightening) for Case 2.
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Clinical Papers

Retrospective Photographic Review of Nontattoo Indications Treated by Picosecond Laser

March 1, 2020
Retrospective chart and photographic review of 233 patients treated with PicoWay and Resolve handpieces for nontattoo indications. Blinded review of treatment outcome showed that every type of skin lesion exhibited improvement; epidermal nevi exhibited the greatest improvement with treatment and acne scarring the least improvement.
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Clinical Papers

A Prospective Study of Fractionated Dual-Wavelength Picosecond Laser in Treating Acne Scars

January 21, 2020
18 subjects with acne scarring underwent 6 full-face treatments with the Resolve 532 nm and 1064 nm handpieces. Evaluation by two dermatologists showed significant improvement after the 1st treatment (p
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Clinical Papers

Histology of ex vivo skin after treatment with fractionated picosecond Nd:YAG laser in high and low-energy settings

January 3, 2020
Biopsy samples from East Asian subjects were treated with either a Resolve 532-nm handpiece or a Resolve 1064-nm handpiece and examined for laser-induced optical breakdowns and intradermal laser-induced cavitations. Superficial, intra-epidermal LIOBs were seen in skin treated with higher laser energies. Deep, intradermal LICs were seen in skin treated at lower energies.
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Clinical Papers

Treatment of Erythematotelangiectatic Rosacea With Pulsed-Dye Laser and Oxymetazoline 1.0% Cream: A Retrospective Study

January 1, 2020
A retrospective study of several male and female patients with ET rosacea treated with both PDL treatments and daily oxymetazoline cream. A blind evaluation by board-certified dermatologists showed the overwhelming majority of subjects achieved at least a two-point clearance in telangiectasias.
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