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Clinical Papers

A Prospective Study of Fractionated Dual-Wavelength Picosecond Laser in Treating Acne Scars


18 subjects with acne scarring underwent 6 full-face treatments with the Resolve 532 nm and 1064 nm handpieces. Evaluation by two dermatologists showed significant improvement after the 1st treatment (p<0.05) that persisted to the 3-month follow-up. 

Reference: Yang CS, Huang YL, Cheng CY, Hu S, Chang SL, Lee MC. Lasers Surg Med. 2020 Jan 21.

Study Details:

  • 18 subjects (10 males, 8 females) with acne scarring, skin phototypes III-IV and mean age 30.8 (range 22 - 45) years underwent 6 Resolve treatments
  • At each session: full-face treatment with the 532 nm handpiece at 0.3–0.5 J/cm2 fluence and 5Hz frequency, followed by full-face treatment with the 1064 nm handpiece at 1.5–1.9 J/cm2 fluence and 8Hz frequency. The 1064 nm handpiece was then applied to areas of scarring with high fluence (2.1–2.5 J/cm2)
  • 2 dermatologists assessed outcome using the Goodman and Baron's quantitative global acne scarring grading system (GSS)

Study Results:

  • Significant improvement after the 1st treatment (p<0.05) that persisted to the 3-month follow-up
  • Subject assessment, using a 5-point Visual Analog Scale, showed improvement from average score of 4.28 at baseline reduced to 2.00 at follow-up
  • Transient erythema and swelling, some purpuric spots lasting 2-3 days
  • No patient complaints of hyper- or hypo-pigmentation or scarring