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Clinical Papers

High versus moderate energy use of bipolar fractional radiofrequency in the treatment of acne scars: a split-face double-blinded randomized control trial pilot study


PubMed Reference: Phothong W, et al. Lasers Med Sci. 2016 Feb.

Study Details: 

  • 30 subjects (17 males, 13 females) with mild to moderate atrophic acne scars
  • Left and right facial sides were randomly assigned for different energy (moderate energy of 60 mJ/pin or high energy of 100 mJ/pin)
  • 4 bipolar fractional RF treatments at 1-month intervals
  • Assessment of global acne scarring score (GASS) for each facial side (dermatologist blinded to treatment energy).

Study Results: 

  • Mean GASS of high energy side and moderate energy side was significantly reduced at 1-, 3-, and 6-month follow-up visits (p<0.001).
  • Similar rate of PIH on both sides with most cases mild to moderate in intensity and spontaneously resolved within 4 weeks.