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100+ indications cleared in 10 medical specialties, including dermatology, plastic surgery, and gynecology.1

Imagine having one system designed for numerous procedures that require excision, incision, ablation, coagulation, and resurfacing of soft tissue. It’s here. With the CO2RE® system, you can precisely target and efficiently treat the skin with control. 

  • Treat multiple skin layers in one pass
  • Perform full and fractional resurfacing
  • Enhance coagulation
  • Encourage neocollagenis
Core Model_Face


Industry-first internal scanner optimized for numerous individualized treatment applications

The world's most wanted energy-based treatment2

Co2re treatment photo


  • "One of CO 2 RE’s advantage is the handpiece, which is very easy to hold. In comparison to other fractional handpieces the CO 2 RE handpiece is thin, lightweight and easy to maneuver around the skin during treatments."
    E. Victor Ross, MD
    Dermatologist San Diego, CA
  • "We’ve been very happy with the results that we’ve seen using CO 2 RE. It has a lot of versatility and we find it works well for both fractionated ablative resurfacing as well as traditional ablative resurfacing."
    Brian Zelickson, MD
    Dermatologist Edina, MN
  • "The CO 2 RE can deliver superficial ablative treatments at variable densities, for a peel-like effect, as well as deep ablative treatments for dermal remodelling."
    Moshe Lapidoth, MD
    Dermatologist Israel
  • “For my practice, we selected the CO2RE CO2 device because it is so versatile with traditional and fractional resurfacing, which means we can treat a wide range of conditions. Adding it to our practice has been easy - it has an excellent graphic interface, as well as a small footprint - and has expanded our patient offerings.”
    Hayes B. Gladstone, MD
    Dermatologic Surgeon, San Ramon, CA.

Give your patients positive experiences and outcomes.

CO2RE treatments are fast and require limited downtime. 

The system delivers proven, predictable, visible results across indications1-4, including: 

  • Enhancing skin tone and texture through skin resurfacing

  • Reducing the effects of the sun and aging on the skin

  • Smoothing out fine lines, wrinkles, and surgical and acne scars


Gain unparalleled treatment flexibility that can help your practice grow.

Designed from the inside out to be a comprehensive work station:

  • CO2RE Aesthetics for skin resurfacing, from superficial to deep skin treatments, including several options and combinations tailored for your patients’ needs. 
  • CO2RE Surgical for a true, continuous wave with efficient skin coagulation after the surgical cut.
  • CO2RE® Intima for gynecology applications, enabling you to broaden your portfolio offering.


  • Light Peel
  • 20-40 µm
  • Level with Stratum Comeum
  • Complexion refresher


  • Epidermal and dermal resurfacing
  • Coagulation
  • 100-200 µm
  • Improve skin tone and texture



  • Deep fractional resurfacing
  • Deeper level coagulation
  • 500-700 µm
  • Improve scars, fine lines and wrinkles


  • Combination of superficial and deep fractional resurfacing
  • Superficial texture variations
  • Fine lines and wrinkles
  • Before
    6 weeks after 1 treatment
    6 weeks after 1 treatment
  • Before
    After 3 treatments
    After 3 treatments
  • Before
    After treatment
    After treatment
  • Before
Enable your practice to address an array of in-demand treatments.

52 million patients6,7

Wrinkle treatments

15 million patients6,7

Pigmentation treatments

15 million patients

Scar treatments

Ready to expand your practice’s treatment versatility and market reach?

  1. CO2RE Laser System 510(k) clearance (K151655), September 2015. 
  2. Mahlberg MJ. Rhinophyma—CO2RE Laser. Candela, data on file, 2015. 
  3. Friedman D. Ablative fractional skin resurfacing and facial scar reduction with the CO2RE device. Candela, data on file, 2015.
  4. Arroyo C. CO2RE laser for burn scar and striae distensae patients. Candela, data on file, 2016. 
  5. CO2RE before and after photos. Candela, data on file. 
  6. 2013 U.S. Census Bureau, Population Division, June 2014.
  7. Internal Syneron Candela estimation.
  8. Proprietary Syneron Consumer Survey, 2015.
  9. American Society for Aesthetic Plastic Surgery. Cosmetic Surgery National Data Bank Statistics, 2017. Page 4. Available at Accessed on <Month date>, 2019.