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Clinical Papers

Successful treatment of pigmentary disorders in Asians with a novel 730-nm picosecond laser


Two Korean females with multiple freckles on the face (Case 1) and melasma, freckles, lentigines and erythema (Case 2) underwent a single PicoWay 730 nm picosecond laser treatment and were evaluated at 6 weeks post‐treatment. Independent evaluation of global assessment, by 2 dermatologists, indicated excellent response (75–94% lightening) for Case 1 and good response (50–74% lightening) for Case 2.

Reference: Lee SJ, Han HS, Hong JK, Park KY, Seo SJ. Lasers Surg Med. 2020 Mar 14.

Study Details:

  • Korean female (age 21 years, Fitzpatrick skin type III) with multiple freckles on both cheeks and periorbital area
  • Single PicoWay 730 nm picosecond laser treatment with fluence of 1.4 J/cm2, 3 mm spot size and single pass with minimum overlap 
  • At 6 weeks post‐treatment, independent evaluation of global assessment, by 2 dermatologists, indicated excellent response (75–94% lightening)

Study Results:

  • Korean female (age 49 years, Fitzpatrick skin type IV) with melasma, freckles, lentigines and erythema on both cheeks and the zygomatic area
  • PicoWay 730 nm laser treatment with fluence of 1.7 J/cm2 and 3 mm spot size on the disseminated freckles and lentigines and 1064 nm laser treatment, with low fluence of 0.6 J/cm2 and 6 mm spot size for the rest of the face
  • At 6 weeks post‐treatment, independent evaluation of global assessment, by 2 dermatologists, indicated good response (50–74% lightening)