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Clinical Papers

Retrospective Photographic Review of Nontattoo Indications Treated by Picosecond Laser


Retrospective chart and photographic review of 233 patients treated with PicoWay and Resolve handpieces for nontattoo indications. Blinded review of treatment outcome showed that every type of skin lesion exhibited improvement; epidermal nevi exhibited the greatest improvement with treatment and acne scarring the least improvement.

Reference: Mehrabi JN, Friedman O, Al-Niaimi F, Artzi O. J Cosmet Dermatol. 2020 Mar;19(3):612-621.

Study Details:

  • Retrospective chart and photographic review of 233 patients (195 females and 38 males) treated with PicoWay and Resolve handpieces for nontattoo indications (i.e. pigmented lesions, acne scars)
  • Number of treatments and parameters were compiled by clinical indication
  • Follow-up ranged from 3 to 9 months post final treatment
  • 2 blinded, independent physicians evaluated treatment outcome, using a visual analog scale consisting of six levels of treatment response (Grade 0, 0%-5% change to Grade 5, 100% improvement)

Study Results:

  • While every type of skin lesion exhibited improvement, there was variability observed in the response to treatment;  epidermal nevi exhibited the greatest improvement with treatment, while acne scarring demonstrated the least
  • Average number of treatments for all lesions was 3
  • Transient pigmentary changes, purpura, blistering were observed. No scarring occurred